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C1q/TNF-related protein 5 upregulates 12/15-LOX through STAT6 signaling to accelerate the development of atherosclerosis, while inhibition of 12/15-LOX reduces LDL oxidation and improves atherosclerosis

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Inhibiting glucagon release: By reducing the release of glucagon, a hormone that raises blood sugar levels, Semaglutide helps maintain better glucose control

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Physical activity Regular movement, particularly resistance training, supports muscle maintenance and metabolic health during weight loss

Why GLP-1 matters for metabolic health cannot be overstated