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Further analyses revealed that both CBSA-induced MN rats and IMN patients displayed increased mRNA expression of AHR and its downstream genes CYP1A1 , CYP1A2 , and CYP1B1 , accompanied by decreased cytoplasmic AHR and increased nuclear AHR protein expression in renal tissue ( Figure 3 ) [132]
Typically, dermal fillers will be metabolized within 6-12 months when a touch up injection can be performed to maintain this volumization
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