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When to reassess If GI symptoms worsen instead of improving over the first 2-3 weeks of a step, if you cannot keep food down, or if you have severe persistent abdominal pain (especially with back radiation), pause and consult a qualified clinician

Given that the placental mitochondrial fusion is impaired in PE (8) and that the expression of the fusion protein OPA1 was reduced in human inflammatory PE placentas (Fig 1H), we examined the expression of OPA1 in all conditions

Methods Participants The sample consisted of 37 new referrals to the PEPP (Prevention and Early Intervention for Psychosis Program) at London Health Sciences Center between April, 2017 and January, 2018 (see Supplementary Fig