Start the dietary elimination phase (remove eggs, cruciferous vegetables, garlic, onions, carbonated drinks, sugar-free gum)
Yang B, Gelfanov VM, El K, Chen A, Rohlfs R, DuBois B, et al
Insulin requires extreme caution with Retatrutide
Annual Costs (2025) Retail Pharmaceutical (Wegovy/Mounjaro as proxies): Without insurance: $12,000-16,800/year With insurance coverage: $1,200-3,600/year (copays) Retatrutide will likely price similarly when approved Research Peptide Suppliers: Maintenance dose (4mg weekly): $3,600-6,000/year Higher dose (8mg weekly): $7,200-12,000/year Requires self-sourcing from suppliers like Red Fox Peptides (third-party HPLC/MS testing, 98%+ purity verification, with delivery within 2-4 days for Canadian customers) Dose Reduction Strategies Many patients successfully maintain on lower doses than required for active weight loss: Lost weight on 12mg weekly
powder tolerates short-term temperature swings State Reconstituted (Liquid Form) Storage 35.6-46.4F (2-8C) (refrigerator) Notes Use within 2-4 weeks
Dosage and administration Semaglutide is typically injected once weekly, with a gradual dose escalation to reduce side effects