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In conclusion, hemeHPX, which regulates cell iron homeostasis and proliferation/cell growth, is taken up by clathrin-mediated endocytosis and raises intracellular ferrous iron safely for the IRE/IRP system of translational regulation

Experimental doses in humans have ranged from 2-5mg administered twice weekly subcutaneously

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A major characteristic of SARS-CoV-2 infection is oxidative stress, which leads to inflammation and vascular dysfunction