Eli Lilly, which makes Zepbound and Mounjaro, just announced phase 3 clinical trial results for its new medication, retatrutide, and it could become the most effective weight loss medication
Signs of potential degradation or contamination include: Discolouration yellowing, browning, or any unusual colour change Clumping or caking which may indicate moisture ingress Visible particulates or foreign matter Unusual odour though peptides are generally odourless, any detectable smell may indicate microbial contamination After reconstitution , a degraded or contaminated solution may appear cloudy, discoloured, or contain visible particles
For something chronic, people don't want their lives running on protocols
However, these were mostly mild to moderate in intensity and often decreased over time
As of 2025, retatrutide has not received MHRA or EMA marketing authorisation in the UK and remains in Phase 3 clinical trials
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