Am J Cardiol
Significance This systematic review highlights the potential therapeutic impact of GLP-1 receptor agonists in reducing substance use disorders in adult patients
Among these, osteoprotegerin (OPG), receptor activator for nuclear factor-B ligand (RANKL), and receptor activator for nuclear factor-B form a triangular relationship that regulates osteoclast differentiation, activation, and apoptosis
Beyond bone health, the effects of GLP-1Ra on musculoskeletal health remain to be elucidated [82]
GLP-1: Glucagon-Like Peptide-1 An incretin hormone that stimulates insulin secretion, reduces glucagon release, slows gastric emptying, and Suppresses appetite, aiding weight loss
Sublingual formulations Sublingual semaglutide and orally disintegrating tablets like tirzepatide ODT are among the most travel-friendly GLP-1 options