The evidence is starting to pile up that Ozempic and other GLP-1 medications could help people with substance abuse disorders.
Most of what shows up in trial data is gastrointestinal and most of it is tied to dose escalation rather than long term stable use, which is an important distinction most people dont know going in
Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Losos M, Tugwell P: The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses
Some clients find that it is easiest to give their dog an injection while he is eating a meal
GLP-1 drugs are remarkable, but they are not magic medical pixie dust.
(4) Intracellular TAAR1 activation: Elevated cytoplasmic tyramine activates trace amine-associated receptor 1 (TAAR1), promoting signaling pathways that result in phosphorylation of the NET transporter, modify transporter function to cause it to switch to reverse transport mode (rNET)