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Additionally, LRG is upregulated in severe knee Osteoarthritis and may be a key player in joint inflammation and fibrosis in this condition 63

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The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper

It acts by modulating apoptosis, autophagy, oxidative stress, and inflammatory responses through key signaling pathways

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Espinosa-Diez C, Miguel V, Mennerich D, Kietzmann T, Snchez-Prez P, Cadenas S, et al