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Accessed 24 March 2025

This primary analysis was designed to reflect routine clinical practice, in which patients frequently receive multiple or sequential classes of diabetic medications

Zhou et al., 2015

While the largest percentage of intracellular iron is tightly bound to or incorporated into proteins as a cofactor or for storage, small portion of intracellular iron resides in the cytosol and intracellular organelles (e.g., lysosomes) and constitutes a redox-active liable iron pool, which regulates programmed cell death including ferroptosis 42

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