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This may suggest that thyroid abnormalities may have a negative impact on patients lipid profile, which may increase the risk of CVD [38]

The structural modifications were designed to improve GHSR-1a selectivity and reduce interaction with receptors driving the adrenal and lactotroph responses

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However, the decreased HDL cholesterol and apoA1 concentrations induced by modified fasting are contradictory to that reported in previous studies [38, 40] which showed that these parameters increased during the zero-calorie fasting period

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