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In terms of weight loss, cotadutide 200 g produced effects similar to liraglutide, while the 300-g dose resulted in greater weight reduction

It's not really changing the course of the disease

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It raises crucial questions about the sustainability of treatment effects and the practical implications of potentially indefinite therapy

Additionally, the interaction between substance abuse and depression may worsen depressive symptoms and its prognosis, leading to a vicious cycle that further complicates metabolic health [48]

Sodium-glucose cotransporter 2 (SGLT2) inhibitors with proven benefits for HF should be used first in patients with HF regardless of HbA1c levels and should be maintained as long as there are no contraindications or side effects (RCT, General)