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Thethi TK, Pratley R, Meier JJ

As the body responds to the microneedling punctures, the PRP works as an added boost of healing by encouraging collagen and elastin production in the targeted area

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Recommended dosage: 0.05% 0.5% in final cosmetic products

In the ischemia/reperfusion-induced fibrosis C57BL/6J mouse model, transcriptomic and metabolomic analyses showed that dapagliflozin treatment mitigated accumulation of tricarboxylic acid (TCA) circulating metabolites and up-regulation of inflammation in fibrotic renal cortical tissue