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One hypothesis proposes that muscle insulin resistance results from decreased mitochondrial fatty acids oxidation

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10.1016/s0378-5955(03)00259-4 36 Musial-BrightL.FenglerR.HenzeG.Herniz DrieverP

Early Triage: CTI correlates with both borderline ABI (0.900.99) and clinical PAD, outperforming traditional markers to capture overlapping inflammatory and metabolic pathways

Adipose tissue (body fat) is metabolically active and produces pro-inflammatory substances called adipokines, including interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-)