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Start at 2.5mg once weekly

Experimental mice were randomly allocated from litters to each experimental cohort and the sex distribution was as follows: wildtype (WT) Pla2g6 + / + (3 males

They are not interchangeable, and the current evidence does not support using research peptides as a substitute for evidence-based HRT where HRT is clinically indicated

Subpockets A and B are also mostly hydrophobic and with only a few polar groups available to make polar interactions with the ligand