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At 24 h post seeding, medium was removed to waste, and cells were treated with 100 L of metformin (10 mM) or vehicle control (H 2 O) diluted in cRPMI and incubated at 37C in 5% CO 2 /95% humidified air

For instance, those dual effects are triggered by teriflunomide, which may thus prove useful in the treatment of anemia in patients with malignancy [489]

The long-term profile requires patience and ongoing monitoring