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Vomiting Vomiting was reported in about 30.9% of patients in the OASIS 4 trial, compared to 5.9% on placebo, and was more common during the dose-escalation period

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Sources Mounjaro KwikPen 10mg solution for injection in pre-filled pen, emc [accessed 16 October 2025] Obesity, NHS [accessed 16 October 2025] Once-Weekly Semaglutide in Adults with Overweight or Obesity, NEJM [accessed 16 October 2025] Tirzepatide Once Weekly for the Treatment of Obesity, NEJM [accessed 16 October 2025] Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen, emc [accessed 16 October 2025] Patient Reviews Related Weight Loss Treatments Further Reading on Weight Loss Do Appetite Suppressants Work

Payers are left to find a balance between coverage and affordability