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Timing medication administration thoughtfully may also minimize digestive disruptions

Patients should use enteric-coated forms only

The researchers identified the bacterial caseinolytic protease (ClpP) as the ADEP target, demonstrating that ADEPs bind to ClpP, activate the otherwise inactive Clp-protease complex, and disrupt essential bacterial protein regulation, potentially accounting for their potent antibacterial effects

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Adequate hydration helps mitigate gastrointestinal discomfort, supports renal function, and prevents dehydration-related complications