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Cardiovascular outcomes and risks after initiation of a sodium glucose cotransporter 2 inhibitor: results from the EASEL population-based cohort study (Evidence for Cardiovascular Outcomes With Sodium Glucose Cotransporter 2 Inhibitors in the Real World)

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Some patients experience breakthrough hunger or minimal metabolic effect at subtherapeutic doses, leading to frustration or incorrect assumptions about individual responsiveness

Verma S, Al-Omran M, Leiter LA, Mazer CD, Rasmussen S, Saevereid HA, Sejersten Ripa M, Bonaca MP: Cardiovascular efficacy of liraglutide and semaglutide in individuals with diabetes and peripheral artery disease