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For the SNcVTA analysis (1.32 mm posterior to bregma 2.56 mm), one in every 11 sections (four total) was selected and processed for TH and EBF3 immunofluorescence

Targeting astrocytes in major depression

Avoid layering copper peptides directly with strong acids or pure vitamin C (ascorbic acid)

Using a long-term HFD-fed mouse model of NAFLD, we demonstrated in this study that NAFLD development occurs concomitantly with dysregulated hepatic glutathione homeostasis characterized by decreased GSH and increased GSSG, and increased TNF protein levels in both the circulation and the liver

Regularly, astrocytes are the main source of NO, however, it has been shown that NT2 neurons can produce NO and therefore increase levels of cGMP (Denninger and Marletta, 1999)