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The methionine overload would tend to decrease basal hyperhomocysteinemia rather than cause a further increase in basal hyperhomocysteinemia in patients bearing remethylation defects such as folate deficiency (associated or not with the C677T mutation of the MTHFR gene) (Durand et al, 1997a

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They protect the uterus but do not provide the same brain benefits

Metabolic modulators Metabolic modulators such as 2-deoxy-D-glucose (2-DG), which acts as an inhibitor of glycolysis, have been shown to reduce the expression of terminal exhaustion markers such as Tim-3 and LAG-3 in T cells while increasing T cell persistence, suggesting that the strategy of short-term inhibition of glycolysis preserves T cell exhaustion without compromising their effector functions and shows promise as a potential metabolic intervention strategy to maintain the antitumor activity of T cells [25]

This technology can identify specific compounds by their exact molecular mass and fragmentation patterns