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Kalen A, Appelkvist EL, Dallner G

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Upon activation, the NLRP3 inflammasome promotes autocatalytic cleavage of procaspase-1 into its active form, caspase-1, which subsequently processes the pro-inflammatory cytokines pro-interleukin-1 and pro-interleukin-18 into their mature forms

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Bacteriostatic water (not sterile or plain water) is the correct diluent because its benzyl-alcohol preservative supports the multi-dose beyond-use window