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Lowe TL, Cohen DJ, Miller S, Young JG: Folic acid and B 12 in autism and neuropsychiatric disturbances of childhood

Clinical translation would require trials in cardiac patient populations with appropriate safety monitoring given theoretical concerns about blood pressure effects and vascular remodeling

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Various countries have introduced labeling of foods to help people adhere to these guidelines by flagging foods that are high in fats, sugars, and salt (HFSS)

Ntambi JM, Takova TJD

The article adds that clinical evidence shows slower titration improves adherence and long-term sustainability, which is why the pace is set by the prescriber rather than chosen by the patient