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3 It was approved by the US FDA in 2023 to treat obesity (Zepbound , Eli Lilly and Company, Indianapolis, IN, USA) which was initially approved to treat type 2 diabetes in 2022 (Mounjaro , Eli Lilly and Company) (Table 1)
Laboratory diagnostics of the serum, urine or muscle acetylcarnitine level can be performed to diagnose L-carnitine deficiency with certainty
Patient education about dye coloration also reduces anxiety and confusion
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they promote vasodilation by enhancing NOS activity, promoting NO production, increasing cyclic guanosine monophosphate (cGMP) levels, maintaining NO-cGMP pathway activity, down-regulating arginase II protein expression, and reducing competitive consumption of L-arginine