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Thats why the treatment-regimen estimand (aka intention-to-treat analysis) is more meaningful for clinical relevance

But magnesium does play an important supporting role in the bigger picture of health

doi: 10.7759/cureus.51655 56 TroshnevaA

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Patients were randomized and treated as soon as possible after arrival in the hospital, once their clinical condition had stabilized and their hemodynamic status had been carefully evaluated