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Jo D, Choi SY, Ahn SY, Song J (2025) IGF1 enhances memory function in obese mice and stabilizes the neural structure under insulin resistance via AKT-GSK3-BDNF signaling

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Neuroprotective properties A unique feature of methylene blue is its ability to penetrate the blood-brain barrier and accumulate in the brain, which has led researchers to investigate the potential utility of this agent for the treatment of neurological disorders

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The compound itself is off-patent and unprotectable