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Collagen in the dermis generates dense, rope-like bundles, serves as a scaffolding network for skin cells, anchors blood vessels, hair follicles, and sweat glands, and promotes the formation of elastin (stretch) and hyaluronic acid (hydration)

Allergic reactions are rare but can be severe, requiring immediate medical attention

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Journal of Biochemical and Molecular Toxicology , 38 , e23537

Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93fes, STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytes