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This timeframe aligns with the gradual nature of biological processes, which occur over weeks to months, not days

Absorption and metabolism Pharmacokinetic studies have shown that LA (50600 mg p.o.) is completely absorbed within 3060 min (half-life: 30 min), which leads to the attainment of the highest concentration of LA in the bloodstream [51]

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One serious adverse event was reported: a severe event of appendicitis with onset 27 days after icodec administration, assessed by the investigator to be possibly related to study product and with an outcome of recovered/resolved on the same day after surgical intervention