(127) have shown that circulating IGF-I levels are related to the histological stages of MASLD

Common Side Effects (Both Medications) Gastrointestinal Effects (Most Common): Nausea (Zepbound: 25-29%, Wegovy: 24-44%) Diarrhea (Zepbound: 19-21%, Wegovy: 7-30%) Vomiting (Zepbound: 12%, Wegovy: 24%) Constipation (Zepbound: 12-17%, Wegovy: 14-24%) Abdominal pain or discomfort Indigestion and acid reflux General Side Effects: Fatigue or tiredness (approximately 4% of patients) Headache (more common with Wegovy) Dizziness Hair loss (temporary in most cases) Injection Site Reactions: Redness, itching, or bruising at injection site Slightly more common with Zepbound Managing Common Side Effects The good news is that most side effects are: Mild to moderate in severity Most pronounced during the initial weeks of treatment Tend to decrease as your body adjusts to the medication Manageable with proper strategies Practical Tips to Minimize Side Effects: Start Low, Go Slow: Both medications use gradual dose escalation specifically to minimize side effects Dietary Modifications: Eat smaller, more frequent meals

But as brand-name makers and telehealth platforms race to normalize and expand access, regulators on both sides are warning of a parallel surge in counterfeit, compounded, and black-market versions
Individuals taking Ozempic should be monitored for DVT-related symptoms and seek medical treatment immediately if they appear
The largest CV benefits were observed for adults with frailty
Medicare Advantage: Can I Have Both