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Considering that OSAS patients often present with multiple comorbiditiessuch as hypertension, coronary artery disease, and diabetesfurther large-scale, long-term follow-up studies are needed to clarify tirzepatides safety in multimorbid populations (63, 64)

The savings over a full year of treatment can reach $7,800 to $13,800

Offer alternative treatment plans When FDA-approved GLP-1s arent accessible, consider: Non-GLP-1 pharmacologic options: Bupropion-naltrexone ER (Contrave ) Phentermine-topiramate ER (Qsymia ) Orlistat Lifestyle-based programs: Structured weight management programs

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"I urge them to speak with their local GP about the options that they have for supporting their weight change," she said