This allows CHAC1 to post-translationally regulate protein activity by binding and cleaving specific -glutamyl amino acids ( Although CHAC2 enzymes in Leishmania major were shown to degrade only reduced and not oxidized glutathione, this specificity has yet to be confirmed for CHAC1 ( CHAC2 is both evolutionarily older and structurally distinct from CHAC1
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This spatial framework has been able to specify a programme of interventions that provide a top-down control of urban transformations (e.g., green streets, retention areas)
