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Consequently, maintaining the therapeutic effects of GLP-1R agonism requires a long-term dosing regimen, much like medications used for other chronic conditions, such as statins for cholesterol control, ACE inhibitors and beta-blockers for blood pressure, or warfarin for blood thinning

doi: 10.1016/j.cmet.2006.01.004 3 PykeCHellerRSKirkRKrskovCReedtz-RungeSKaastrupP.GLP-1 receptor localization in monkey and human tissue: Novel distribution revealed with extensively validated monoclonal antibody

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Brent James, M.D., an expert on clinical quality improvement and patient safety, told Fierce Healthcare in an email that medicine has a long history of overreacting to a new drug and then quietly moving on when the full set of circumstances become known

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