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Semaglutide is an FDA-approved medication for obesity and diabetes that helps people lose about 15% of their weight when combined with lifestyle changes

Drug availability, indications, and insurance coverage can change over time

If you notice a hard lump at an injection site that does not resolve within two weeks, you may be developing lipohypertrophy from inadequate rotation

Missed dose: If you miss a dose, do not attempt to manage this independently

If the triad is not present, then hypoglycemia is not causing the patients symptoms

It is hypothesized that with continued use and continued titration of insulin, superior reductions in A1C would be seen with an intensive insulin therapy compared to GLP-1 RAs