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We modeled three pricing scenarios based on CMS negotiated rates and anticipated generic competition: Low scenario (generic semaglutide becomes available): $2,940 per year Mid scenario (blended Wegovy, Mounjaro, Zepbound): $3,600 per year High scenario (newest brands before generics): $4,200 per year The mid scenario projects the following: Years 1-2 (2027-2028): Ramp-up phase

The mean age for this group was 47 years old

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The appetite suppression gives them a "quieter" food environment so that their existing discipline translates efficiently into a sustained calorie deficit

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