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Conflict of Interest Statement The authors are employees of nference, inc., which conducts research collaborations with various biopharmaceutical companies, including Eli Lilly and Company and Novo Nordisk A/S, whose GLP-1 receptor agonist products (tirzepatide and semaglutide) are included in this study

Differences in organ distribution of methylene blue are mainly responsible for the different pharmacokinetics after oral and IV administration

Starting dosage and dose adjustments are based on the type of semaglutide used and the patients age and weight

J.HlscherC.et al (2013)

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These are in varying phases of preclinical or early clinical study