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In the Ahn et al
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H., & Joosten, S
PMCID: PMC6388891
75 While standard melatonin supplements rapidly increase blood melatonin levels and can shorten the time needed to fall asleep, newer extended-release formulations have been found to sustain higher melatonin levels through the night in healthy individuals and hold promise for their potential to better maintain sleep through the night
Your body adjusts to some degree over time, but the effect does not disappear entirely
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