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7 Due to its longer half-life, semaglutide has prolonged CNS effects, regulating appetite and metabolic processes

Prescribers should monitor mental health, particularly in patients with psychiatric histories

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The most frequently reported side effects in this study were mild to moderate nausea, diarrhea, vomiting, and constipation

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If you're also taking medications that can worsen dehydration (such as diuretics, SGLT2 inhibitors, or NSAIDs), discuss a sick-day management plan with your healthcare provider