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We therefore postulated that IGF-1R mAbs could represent a viable therapeutic tool to target IGF-1 action, and potentially mimic the beneficial effects associated with diminished IGF-1 signaling observed in animal models

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E-mail: [email protected] Date of Received: 28-12-2010 Date of Accepted: 06-06-2011 Available Online: 15-08-2011 Abstract The primary role of glutathione transferase is to defend an organism from toxicities through catalyzing the reaction of glutathione (GSH) with potentially toxic compounds or metabolites to their chemically and biologically inert conju-gates

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