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We next observed that at 0.5% O 2 hypoxia, proliferation of HeLa cells expressing LUC was slower compared to that at 21% O 2 but Cr GPDH expression allowed substantial growth rescue after two days following induction of Cr GPDH expression with Dox ( Figure 4f-h )

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Bischoff SC, Barbara G, Buurman W, Ockhuizen T, Schulzke J-D, Serino M, et al

The maintenance of glycolysis in xCT high cancer cells is essential for constituting a potential treatment strategy to induce ferroptosis [Figure 2A]