The functionality of mitochondria, which is responsible for biosynthesis and signal transduction, can be compromised by various diseases, resulting in mitochondrial dysfunction that often coincides with the progression of pathological conditions [8, 9]
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That said, compounded GLP-1s dont have the same large-scale, brand-specific clinical trial data as commercially manufactured versions
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The absence of RCTs among the included studies is a notable limitation, as observational and retrospective designs may be more susceptible to confounding, selection bias, and variability in data quality
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