In 2016, Alize Pharma achieved positive results in a Phase II trial with AZP-531 , a first-in-class unacylated ghrelin peptide analog, but was unable to advance the treatment further
Clinical trials have shown that people using Tirzepatide for weight loss have seen significant reductions in body weight between 15% and 22.5% on average over 72 weeks
Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on April 15th, 2026
Broader translational hurdles: outcome measures and trial design
If your primary treatment goal is weight loss rather than diabetes management, ask your prescriber about Wegovy , which contains the same active ingredient at higher doses (up to 7.2mg) specifically designed for chronic weight management
Common side effects currently include: Diarrhoea Vomiting Altered sense of taste If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme
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