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Patients who discontinued it regained a significant portion of the weight, which is consistent with the understanding that obesity is a chronic condition requiring ongoing management rather than a short-term problem with a finite treatment window

For individuals with diabetes, a combined creatinine/cystatin C estimate of eGFR should be considered in settings where the creatinine-based eGFR may be unreliable for an individual (see Table 6) [21] [Grade D, Consensus]

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