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FIGURE 3 2.4.2 Lactate Lactate, primarily produced through glycolysis, is crucial for maintaining cardiovascular system homeostasis (Lactate helps in tissue repair, 2023)

Bianca Itariu: declares no conflict of interest relevant to this study

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By contrast, deep-learning-based generative models can now interrogate large chemical-biological datasets to uncover structure-activity relationships, generating novel scaffolds with plausible three-dimensional conformations and tailored engagement of both target and E3 ligase, thereby vastly expanding accessible chemical space [62, 282,283,284,285,286,287]

Cheung, R

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