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Use caution in patients with a history of anaphylaxis or angioedema to other GLP-1 receptor agonists because it is unknown whether such patients will be predisposed to serious reactions with semaglutide

In some embodiments, Sodium Thiosulfate, Potassium Thiosulfate, HMTBa, Oltipraz, D-cysteine, D-methionine, or a combination thereof improves spiral ganglion neuron survival, function, viability, health, growth, or a combination thereof following chemotherapy-induced ototoxicity by at least or about 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, or more than 95%

For the majority of patients, these episodes can last for several hours or days, which makes it difficult to carry out daily activities

Most patients return to their normal activities immediately after treatment