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[2] Choline chloride serves as an essential substrate for phosphatidylcholine and betaine formation, thereby enhancing bile-dependent lipid emulsification and acting as an osmolyte that maintains hepatocyte membrane integrity under oxidative stress

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Risk of Bias assessment of the included articles was conducted using the Risk of Bias version 2 (RoB2) tool ( Statistical analyses We performed all meta-analyses using RevMan (version 5.4, Cochrane Collaboration)

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step 1 trial semaglutide 2.4 mg weight loss nejm 2021 Once-Weekly in Adolescents with Obesity Semaglutide in Adults with Type
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