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Induction of apoptosis: Metformin can also increase the clearance efficiency of the immune system by inducing apoptosis of glioma cells

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Concretely, GPX4 uses GSH as the substrate to reduce phospholipid hydroperoxides (PLOOHs) to hydroxyl derivatives (PLOHs), and oxidizes GSH to GSSH, therefore alleviating the damage of oxidative stress to tumor cells (Stockwell, 2022)

It may offer several health and beauty benefits, including supporting immune function, liver health, and muscle recovery, though more research is needed

(12) Resources [1] Aldini G, Altomare A, Baron G, Vistoli G, Carini M, Borsani L, Sergio F