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Statements Author contributions R-YG and D-TW: conceptualization, supervision, and funding acquisition

Providing direct molecular evidence for this impairment, Deng et al

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Moreover, we also reproduced the reaction of SnCE1 with SUMO1-PA and SUMO3-PA probes with higher efficiency towards SUMO1-PA compared to SUMO3-PA and its efficient deSUMOylase activity cleaving polymeric SUMO2 [26] chains to yield mono-SUMO2 (Fig

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doi: 10.1186/s12916020-01587-w 202 TraberMGStevensJF