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doi: 10.3389/fcell.2022.956274 Summary Keywords cisplatin, premature ovarian failure, apoptosis, protection strategies, research and analysis Citation Li Z, Qi H, Li Z, Bao Y, Yang K and Min Q (2023) Research progress on the premature ovarian failure caused by cisplatin therapy

Transferrin-SPIONs (Tf-SPIONs) bind transferrin receptors (TfR), while lactoferrin-SPIONs (Lf-SPIONs) engage lactoferrin receptors (LRP1), facilitating receptor-mediated endocytosis into tumor cells

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[PubMed: 16904799] (Evaluation of the safety of oral ALA in rats who exhibited no evidence of toxicity except at the highest doses tested [121 mg/kg], which was associated with minor ALT elevations in males and slight changes in liver histology including small droplet fat in periportal regions, but without frank hepatocyte necrosis or inflammation)

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