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The condition involves dysregulation of neurotransmitters, inflammatory mediators, and stress response systems, producing a constellation of symptoms extending far beyond pain to include crushing fatigue, unrefreshing sleep, cognitive dysfunction known as fibro fog, and heightened sensitivity to temperature, sound, and light

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Therefore, we have emphasized the crucial role of the CS and its fine-tuned regulation, which is both enzymatic- and miRNA-dependent, as the primary factor in metabolic cancer flexibility

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