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Yes you have to diet and exercise

Peripheral Cyanosis The discoloration of the feet, often turning purple or bluish, is a result of insufficient oxygen supply to the tissues, a condition known as cyanosis

Gastroenterology 98:A461

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T.Di FrancescoP.FavalliC.CirioloM

Absorption JANUMET XR After administration of JANUMET XR tablets once daily, the median Tmax value for sitagliptin and metformin at steady state is approximately 3 and 8 hours postdose, respectively